וְאָמַרְתָּ֗ יְהוָה֙ אַתָּ֨ה דִבַּ֜רְתָּ אֶל־הַמָּק֤וֹם הַזֶּה֙ לְהַכְרִית֔וֹ לְבִלְתִּ֤י הֱיֽוֹת־בּוֹ֙ יוֹשֵׁ֔ב לְמֵאָדָ֖ם וְעַד־בְּהֵמָ֑ה כִּֽי־שִׁמְמ֥וֹת עוֹלָ֖ם תִּֽהְיֶֽה׃
and say: O LORD, Thou hast spoken concerning this place, to cut it off, that none shall dwell therein, neither man nor beast, but that it shall be desolate for ever.
Read kabbalistic (mystical) interpretation of Jeremiah 51:62: and classical mystical sources.